Intravascular large B-cell lymphoma with cerebral infarction: a report of a difficult-to-diagnose case caused by a thrombus in the auricle of the left atrium
نویسندگان
چکیده
血管内大細胞型B細胞リンパ腫（IVLBCL）はリンパ腫が血管内に増殖する疾患であり，貧血や低アルブミン血症，血清乳酸脱水素酵素の上昇などを呈する．今回我々は，脳梗塞がこれらの症状に先行し，診断に難渋したIVLBCLを経験した．症例は65歳男性．ふらつきで受診し，頭部MRIで多発脳梗塞を認めた．経食道心エコーで左心耳内血栓を認め，心原性脳塞栓症として治療するも，脳梗塞を繰り返した．経過中に微熱が出現し，貧血と低アルブミン血症，血清乳酸脱水素酵素，可溶性IL-2受容体の上昇を認めた．ランダム皮膚生検で，IVLBCLと診断した．化学療法を施行したが，3年後に死亡した．本例は左心耳内血栓を合併し，全身症状が出現するまで心原性脳塞栓症との鑑別が困難だった．抗凝固療法中にもかかわらず，短期間に脳梗塞を繰り返す場合には，IVLBCLも念頭に置く必要がある．
منابع مشابه
Intravascular Large B-cell Lymphoma: A Report of Two Cases
One of the rare variants of extranodal large B-cell lymphoma is intravascular large B-cell lymphoma (IVLBCL). Characteristics of IVLBCL include intraluminal selective proliferation of atypical lymphoid cells in small to medium-sized vessels. The etiologic of IVLBCL is unknown, but due to the growth pattern of this tumor, it is speculated that IVLBCL is caused by a defect in homing receptor of t...
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ژورنال
عنوان ژورنال: Nosotchu
سال: 2023
ISSN: ['0912-0726', '1883-1923']
DOI: https://doi.org/10.3995/jstroke.11132